SCHEMBL21765097

SCHEMBL21765097

CCCc1ccc(Cc2cc(C3CC(C)CC(C)C3)ccc2Cl)cc1

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 19/20 0.44
SLC5A1 P13866 14/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20124375 0.92 SLC5A2 (0.45) SLC5A2SLC5A1
SCHEMBL23453304 0.90 SLC5A2 (0.39) SLC5A2SLC5A1
SCHEMBL20124376 0.89 SLC5A2 (0.54) SLC5A2SLC5A1
SCHEMBL25853276 0.81 SLC5A2 (0.41) SLC5A2SLC5A1
SCHEMBL24981125 0.80 SLC5A2 (0.48) SLC5A2SLC5A1
SCHEMBL20124374 0.80 SLC5A2 (0.46) SLC5A2SLC5A1
SCHEMBL24952274 0.79 SLC5A2 (0.36) SLC5A2SLC5A1
SCHEMBL25665514 0.77 SLC5A2 (0.49) SLC5A2SLC5A1
SCHEMBL20124355 0.77 SLC5A2 (0.59) SLC5A2SLC5A1
SCHEMBL23454053 0.76 SLC5A1 (0.38) SLC5A2SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023006718-A1 USE OF SGLT-2 INHIBITORS FOR THE PREVENTION AND/OR TREATMENT OF CARDIAC DISEASES IN NON-HUMAN MAMMALS EXCLUDING FELINES, IN PARTICULAR CANINES BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2023-02-02 WO disclosed
WO-2023006747-A1 USE OF SGLT-2 INHIBITORS FOR THE PREVENTION AND/OR TREATMENT OF RENAL DISEASES IN NON-HUMAN MAMMALS BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2023-02-02 WO disclosed
WO-2023006745-A1 USE OF SGLT-2 INHIBITORS FOR THE PREVENTION AND/OR TREATMENT OF HYPERTENSION IN NON-HUMAN MAMMALS BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2023-02-02 WO disclosed
WO-2020039394-A1 NEW DRUG COMBINATIONS NOVARTIS AG (CH) 2020-02-27 WO disclosed