Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 4/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | BCL6 | P41182 | 1/20 | 0.45 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9972390 | 0.80 | KDR (0.56) | EPHA2KDREPHB4SRCACHE | |
| SCHEMBL9939708 | 0.76 | KDR (0.51) | EPHA2KDREPHB4JAK3SRC | |
| SCHEMBL22135125 | 0.73 | KDR (0.49) | EPHA2KDREPHB4JAK3SRC | |
| SCHEMBL374465 | 0.71 | FGFR3 (0.62) | KDREPHB4SRCEGFRRAF1 | |
| SCHEMBL30213768 | 0.71 | EGFR (0.51) | JAK2JAK3PTK2EGFRHTR2B | |
| SCHEMBL30213748 | 0.70 | EGFR (0.62) | EGFRERBB2 | |
| SCHEMBL3654890 | 0.70 | RAF1 (0.47) | KDREPHB4JAK2JAK3PTK2 | |
| SCHEMBL3401694 | 0.70 | ALDH1A1 (0.54) | KDRSRCKDM4EALDH1A1HTR2C | |
| SCHEMBL19089351 | 0.69 | ALDH1A1 (0.59) | EPHA2KDREPHB4NPC1KDM4E | |
| SCHEMBL4209736 | 0.69 | EPHX2 (0.54) | NPC1SRCKDM4EALDH1A1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651416-B1 | COMPOUNDS USEFUL FOR TREATING AIDS | ABIVAX (FR) | 2018-05-09 | — | — | EP | disclosed |