SCHEMBL20124624

SCHEMBL20124624

C=Cc1ccc(Cc2cc(C3(O)CC(OCc4ccccc4)CC(COCc4ccccc4)O3)ccc2Cl)cc1

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 11/20 0.37
SLC5A1 P13866 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20274690 0.80 SLC5A2 (0.35) SLC5A2SLC5A1
SCHEMBL20124674 0.78 SLC5A2 (0.44) SLC5A2SLC5A1
SCHEMBL22132975 0.77 OPRM1 (0.40)
SCHEMBL499751 0.77 SLC5A2 (0.40) SLC5A2SLC5A1
SCHEMBL20124718 0.76 SLC5A2 (0.34) SLC5A2SLC5A1
SCHEMBL24333527 0.74 SLC5A2 (0.51) SLC5A2SLC5A1
SCHEMBL19415597 0.74 SLC5A2 (0.44) SLC5A2SLC5A1
SCHEMBL19415603 0.74 SLC5A2 (0.44) SLC5A2SLC5A1
SCHEMBL23030025 0.71 L3MBTL1 (0.32)
SCHEMBL10169592 0.70 SLC5A2 (0.39) SLC5A2SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3318562-A2 BENZYLBENZENE DERIVATIVES AND METHODS OF USE Theracos Sub, LLC (US) 2018-05-09 EP disclosed