Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 2/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL776588 | 0.80 | CYP2D6 (0.44) | TAAR1LMNAADRA2AADRA2CHIF1A | |
| SCHEMBL12954696 | 0.78 | DPP4 (0.42) | TAAR1LMNAADRA2AADRA2CHIF1A | |
| SCHEMBL29820362 | 0.75 | DPP4 (0.43) | TAAR1LMNAADRA2AADRA2CHIF1A | |
| SCHEMBL6911929 | 0.74 | MIF (0.38) | TAAR1LMNAADRA2AADRA2CHIF1A | |
| SCHEMBL12667576 | 0.72 | DPP4 (0.46) | TAAR1LMNAADRA2AADRA2CHIF1A | |
| SCHEMBL12724555 | 0.71 | MIF (0.35) | TAAR1LMNAADRA2AADRA2CHIF1A | |
| SCHEMBL12724553 | 0.71 | MIF (0.35) | TAAR1LMNAADRA2AADRA2CHIF1A | |
| Isopropylbenzene SCHEMBL9790843 | 0.70 | DPP4 (0.43) | TAAR1LMNAADRA2AADRA2CHIF1A | |
| SCHEMBL14812652 | 0.70 | LMNA (0.41) | TAAR1LMNAADRA2AADRA2CHIF1A | |
| SCHEMBL10957460 | 0.68 | ADRA2A (0.43) | TAAR1LMNAADRA2AADRA2CHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3008045-B1 | ANTIBACTERIAL THIAZOLECARBOXYLIC ACIDS | ANTABIO SAS (FR) | 2018-05-09 | — | — | EP | disclosed |