Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.45 |
| ▸ | CHAT | P28329 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27969283 | 1.00 | NFE2L2 (0.50) | NFE2L2TRPA1MAOBCYP19A1MAOA | |
| SCHEMBL1248288 | 1.00 | NFE2L2 (0.50) | NFE2L2TRPA1MAOBCYP19A1MAOA | |
| SCHEMBL27978369 | 0.86 | LOXL2 (0.41) | NFE2L2TRPA1MAOBCYP19A1MAOA | |
| SCHEMBL28130350 | 0.86 | LOXL2 (0.41) | NFE2L2TRPA1MAOBCYP19A1MAOA | |
| SCHEMBL10765758 | 0.84 | NFE2L2 (0.52) | NFE2L2TRPA1MAOBCYP19A1MAOA | |
| SCHEMBL10765753 | 0.84 | NFE2L2 (0.52) | NFE2L2TRPA1MAOBCYP19A1MAOA | |
| SCHEMBL27978430 | 0.82 | LOXL2 (0.42) | NFE2L2TRPA1MAOBCYP19A1MAOA | |
| SCHEMBL27969100 | 0.82 | LOXL2 (0.42) | NFE2L2TRPA1MAOBCYP19A1MAOA | |
| SCHEMBL10761271 | 0.81 | NFE2L2 (0.48) | NFE2L2TRPA1MAOBCYP19A1MAOA | |
| SCHEMBL10761275 | 0.81 | NFE2L2 (0.48) | NFE2L2TRPA1MAOBCYP19A1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3008045-B1 | ANTIBACTERIAL THIAZOLECARBOXYLIC ACIDS | ANTABIO SAS (FR) | 2018-05-09 | — | — | EP | disclosed |