Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 2/20 | 0.52 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | CHUK | O15111 | 1/20 | 0.43 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | PRKX | P51817 | 1/20 | 0.43 |
| ▸ | PRKG2 | Q13237 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20179693 | 1.00 | CHRNB2 (0.53) | CHRNB2CHRNA4HRH1PRKCZROCK1 | |
| Hydrochloric Acid SCHEMBL22031560 | 0.98 | CHRNB2 (0.51) | CHRNB2CHRNA4HRH1PRKCZROCK1 | |
| Hydrochloric Acid SCHEMBL20165250 | 0.98 | CHRNB2 (0.51) | CHRNB2CHRNA4HRH1PRKCZROCK1 | |
| Hydrochloric Acid SCHEMBL20165251 | 0.98 | CHRNB2 (0.51) | CHRNB2CHRNA4HRH1PRKCZROCK1 | |
| SCHEMBL18689816 | 0.89 | CHRNB2 (0.55) | CHRNB2CHRNA4HRH1PRKCZROCK1 | |
| SCHEMBL3574466 | 0.89 | HRH1 (0.66) | CHRNB2CHRNA4HRH1ROCK1ROCK2 | |
| Hydrochloric Acid SCHEMBL15476748 | 0.87 | HRH1 (0.63) | CHRNB2CHRNA4HRH1ROCK1ROCK2 | |
| SCHEMBL14862725 | 0.84 | SLC6A2 (0.53) | HRH1HTR1ASLC6A2 | |
| SCHEMBL7000861 | 0.83 | PRKCZ (0.56) | CHRNB2CHRNA4HRH1PRKCZROCK1 | |
| SCHEMBL3133920 | 0.83 | PRKCZ (0.56) | CHRNB2CHRNA4HRH1PRKCZROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3008045-B1 | ANTIBACTERIAL THIAZOLECARBOXYLIC ACIDS | ANTABIO SAS (FR) | 2018-05-09 | — | — | EP | disclosed |