Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CXCR5 | P32302 | 6/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | MAT2A | P31153 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15506997 | 0.84 | ACHE (0.41) | ACHECXCR5NFE2L2ALDH1A1ERN1 | |
| SCHEMBL20125036 | 0.81 | ACHE (0.39) | ACHECXCR5NFE2L2ALDH1A1ERN1 | |
| SCHEMBL19624995 | 0.80 | ACHE (0.42) | ACHECXCR5NFE2L2ALDH1A1ERN1 | |
| SCHEMBL14198041 | 0.78 | LMNA (0.51) | ALDH1A1SMN1; SMN2KCNH2MAT2A | |
| SCHEMBL20125046 | 0.75 | CD44 (0.46) | CXCR5ALDH1A1 | |
| SCHEMBL19879756 | 0.75 | NPSR1 (0.45) | CXCR5ALDH1A1SMN1; SMN2 | |
| SCHEMBL31227003 | 0.74 | ACHE (0.48) | ACHENFE2L2ALDH1A1ERN1SMN1; SMN2 | |
| SCHEMBL28158271 | 0.74 | ACHE (0.48) | ACHENFE2L2ALDH1A1SMN1; SMN2KCNH2 | |
| SCHEMBL1663012 | 0.74 | ACHE (0.48) | ACHENFE2L2ALDH1A1ERN1SMN1; SMN2 | |
| SCHEMBL12091400 | 0.74 | ACHE (0.48) | ACHENFE2L2ALDH1A1SMN1; SMN2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3318557-A2 | QUINOLONE COMPOUND | Otsuka Pharmaceutical Co., Ltd. (JP) | 2018-05-09 | — | — | EP | disclosed |