Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | RAF1 | P04049 | 3/20 | 0.32 |
| ▸ | BRAF | P15056 | 3/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24857525 | 0.84 | L3MBTL1 (0.47) | L3MBTL1TNKSNUDT1ACKR3 | |
| SCHEMBL15828606 | 0.79 | TNKS (0.43) | L3MBTL1TNKSDRD1NUDT1NTRK1 | |
| SCHEMBL15743211 | 0.79 | L3MBTL1 (0.59) | L3MBTL1TNKSDRD1NUDT1GRM5 | |
| SCHEMBL20801915 | 0.78 | L3MBTL1 (0.39) | L3MBTL1TNKSDRD1NUDT1GRM5 | |
| SCHEMBL20124995 | 0.78 | L3MBTL1 (0.49) | L3MBTL1TNKSNUDT1ADORA2AACKR3 | |
| SCHEMBL2260742 | 0.77 | L3MBTL1 (0.67) | L3MBTL1TNKSNUDT1ACKR3 | |
| SCHEMBL13821670 | 0.76 | L3MBTL1 (0.50) | L3MBTL1TNKSNUDT1ADORA2AACKR3 | |
| SCHEMBL25096433 | 0.75 | GRM5 (0.41) | GRM5 | |
| SCHEMBL3782021 | 0.75 | XDH (0.44) | L3MBTL1DRD1NUDT1RAF1BRAF | |
| SCHEMBL31240834 | 0.75 | L3MBTL1 (0.46) | L3MBTL1TNKSNUDT1EPHB4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3318557-A2 | QUINOLONE COMPOUND | Otsuka Pharmaceutical Co., Ltd. (JP) | 2018-05-09 | — | — | EP | disclosed |