Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.60 |
| ▸ | DDO | Q99489 | 1/20 | 0.60 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CTSV | O60911 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24446610 | 0.84 | CTSV (0.46) | DAODDOPARP1NPEPPSNR3C1 | |
| SCHEMBL14531557 | 0.81 | DAO (0.60) | DAODDOPARP1NPEPPSMAPT | |
| SCHEMBL5769848 | 0.79 | DAO (0.50) | DAODDOPARP1NPEPPSKDM4E | |
| SCHEMBL17345632 | 0.79 | DAO (0.49) | DAODDOPARP1MTNR1AMTNR1B | |
| SCHEMBL23714709 | 0.79 | PARP1 (0.42) | DAODDOPARP1MAPTKDM4E | |
| SCHEMBL5917425 | 0.79 | DAO (0.49) | DAODDOPARP1MTNR1AMTNR1B | |
| SCHEMBL18586039 | 0.79 | PARP1 (0.43) | DAODDOPARP1NPEPPSMAPT | |
| SCHEMBL29751638 | 0.78 | HRH4 (0.49) | DAODDOPARP1KDM4EMTNR1A | |
| SCHEMBL19644194 | 0.78 | PBRM1 (0.45) | DAODDOPARP1MAPTKDM4E | |
| SCHEMBL24453539 | 0.77 | NR3C1 (0.45) | DAODDOPARP1NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3318557-A2 | QUINOLONE COMPOUND | Otsuka Pharmaceutical Co., Ltd. (JP) | 2018-05-09 | — | — | EP | disclosed |