Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.41 |
| ▸ | EIF2AK4 | Q9P2K8 | 3/20 | 0.40 |
| ▸ | COMT | P21964 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15829283 | 0.83 | EIF2AK4 (0.46) | TGFBR1EIF2AK4 | |
| SCHEMBL19737585 | 0.83 | EIF2AK4 (0.39) | PRMT5WDR77TGFBR1EIF2AK4 | |
| SCHEMBL22958682 | 0.72 | CYP1A2 (0.41) | CYP1A2CYP2C9EIF2AK4KDM4EGLA | |
| SCHEMBL21083338 | 0.71 | CYP1A2 (0.42) | CYP1A2CYP2C9PRMT5WDR77TGFBR1 | |
| SCHEMBL26358849 | 0.70 | FLT3 (0.49) | CYP1A2CYP2C9TGFBR1FLT3 | |
| SCHEMBL12998305 | 0.69 | CHEK1 (0.54) | CYP1A2CYP2C9PRMT5WDR77KDM4E | |
| SCHEMBL10238918 | 0.68 | CYP1A2 (0.56) | CYP1A2CYP2C9PRMT5WDR77TGFBR1 | |
| SCHEMBL17055676 | 0.68 | FLT3 (0.58) | CYP1A2CYP2C9PRMT5WDR77ALDH1A1 | |
| SCHEMBL3832037 | 0.66 | CYP1A2 (0.43) | CYP1A2CYP2C9PRMT5WDR77KDM4E | |
| SCHEMBL25148964 | 0.66 | FYN (0.52) | CYP1A2CYP2C9PRMT5WDR77FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200055823-A1 | QUINOLONE COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2020-02-20 | — | — | US | disclosed |
| EP-3318557-A2 | QUINOLONE COMPOUND | Otsuka Pharmaceutical Co., Ltd. (JP) | 2018-05-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055823-A1 | QUINOLONE COMPOUND | HAX1, NQO2, NHERF1 | CYP1A2 252/4885CYP2C9 357/4885PRMT5 3745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.