Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL721648 | 0.81 | GABRA1 (0.52) | PTPN22 | |
| Water SCHEMBL28257828 | 0.80 | GABRA1 (0.50) | PTPN22 | |
| SCHEMBL12829649 | 0.79 | VKORC1 (0.48) | — | |
| SCHEMBL28724813 | 0.79 | PTPN22 (0.46) | PTPN22 | |
| SCHEMBL29886792 | 0.79 | — | — | |
| SCHEMBL2167788 | 0.79 | — | — | |
| SCHEMBL130289 | 0.78 | PTPN22 (0.58) | PTPN22 | |
| SCHEMBL6010301 | 0.78 | — | — | |
| SCHEMBL29354413 | 0.78 | — | — | |
| SCHEMBL2016155 | 0.78 | POLB (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2370422-A1 | THIOCHROMENE DERIVATIVES AS HIP HYDROXYLASE INHIBITORS | Fibrogen, Inc. (US) | 2011-10-05 | — | — | EP | disclosed |
| WO-2011075630-A1 | SUBSTITUTED FUSED ARYL AND HETEROARYL DERIVATIVES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2011-06-23 | — | — | WO | disclosed |
| WO-2010056767-A1 | THIOCHROMENE DERIVATIVES AS HIP HYDROXYLASE INHIBITORS | FIBROGEN, INC. (US) | 2010-05-20 | — | — | WO | disclosed |