Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31148944 | 1.00 | POLB (0.46) | POLBALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL7924277 | 0.81 | POLB (0.46) | POLBALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL28799661 | 0.79 | ERN1 (0.46) | POLBALDH1A1CYP2A6SMN1; SMN2ERN1 | |
| SCHEMBL16414608 | 0.79 | POLB (0.50) | POLBALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL30640504 | 0.79 | GABRA1 (0.52) | POLBALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL8850092 | 0.79 | GABRA1 (0.52) | POLBALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL2012510 | 0.78 | PTPN22 (0.48) | — | |
| SCHEMBL11746597 | 0.78 | CYP2A6 (0.48) | ALDH1A1CYP2A6TSHRHSD17B10TDP1 | |
| SCHEMBL4592248 | 0.78 | ALDH1A1 (0.41) | POLBALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL596646 | 0.76 | POLB (0.57) | POLBALDH1A1CYP2A6TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114685518-B | Organic compounds, mixtures, compositions and organic electronic devices | 广州华睿光电材料有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-114685454-B | Organic compounds, mixtures, compositions and organic electronic devices | 广州华睿光电材料有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-114685518-A | Organic compound, mixture, composition and organic electronic device | 广州华睿光电材料有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-114685454-A | Organic compound, mixture, composition and organic electronic device | 广州华睿光电材料有限公司 | 2022-07-01 | — | — | CN | disclosed |
| WO-2011075630-A1 | SUBSTITUTED FUSED ARYL AND HETEROARYL DERIVATIVES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2011-06-23 | — | — | WO | disclosed |
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | disclosed |
| WO-2000037433-A1 | INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 2000-06-29 | — | — | WO | disclosed |