Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 6/20 | 0.37 |
| ▸ | RAB9A | P51151 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15828716 | 0.82 | L3MBTL1 (0.38) | PARP1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL16502842 | 0.80 | TARBP2 (0.48) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL14161600 | 0.74 | PARP1 (0.41) | PARP1CYP11B1CYP11B2NPC1RAB9A | |
| SCHEMBL10749868 | 0.74 | ALDH1A1 (0.40) | ALDH1A1KDM4EKMT2AL3MBTL1MAPK8 | |
| SCHEMBL11926949 | 0.74 | ALDH1A1 (0.35) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL11063816 | 0.72 | MAPT (0.38) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL12866048 | 0.72 | AOC3 (0.42) | PARP1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL4492232 | 0.72 | MAPT (0.35) | SMN1; SMN2MAPTALDH1A1LMNAGAA | |
| SCHEMBL14363137 | 0.72 | SELL (0.41) | SMN1; SMN2ALDH1A1ATM | |
| SCHEMBL1720148 | 0.71 | PARP1 (0.54) | PARP1CYP11B1CYP11B2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3318557-A2 | QUINOLONE COMPOUND | Otsuka Pharmaceutical Co., Ltd. (JP) | 2018-05-09 | — | — | EP | disclosed |