Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.70 |
| ▸ | LMNA | P02545 | 6/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.69 |
| ▸ | MEN1 | O00255 | 6/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16097533 | 0.87 | RAD52 (0.80) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL16097710 | 0.86 | MAPT (0.69) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL16097706 | 0.86 | ALDH1A1 (0.76) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL15829432 | 0.85 | MAPT (0.65) | ALDH1A1LMNAMAPTNPSR1KMT2A | |
| SCHEMBL1643927 | 0.84 | ALDH1A1 (0.76) | ALDH1A1LMNAMAPTNPSR1KMT2A | |
| SCHEMBL16098653 | 0.83 | KMT2A (0.84) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL5506340 | 0.80 | ALDH1A1 (0.57) | ALDH1A1LMNAMAPTNPSR1KMT2A | |
| SCHEMBL16097379 | 0.80 | WNT3A (0.69) | ALDH1A1LMNAMAPTSMN1; SMN2ALOX15 | |
| SCHEMBL21722001 | 0.80 | MAPT (0.64) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL27000659 | 0.80 | KDM4E (0.69) | ALDH1A1LMNAMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3318557-A2 | QUINOLONE COMPOUND | Otsuka Pharmaceutical Co., Ltd. (JP) | 2018-05-09 | — | — | EP | disclosed |