Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 4/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26769418 | 1.00 | MAOA (0.36) | MAOAMAOBKDM4CTDP1CTSK | |
| SCHEMBL6373802 | 0.85 | MAOA (0.36) | MAOAMAOBTDP1KMT2AMEN1 | |
| SCHEMBL8446924 | 0.83 | MAOA (0.41) | MAOAMAOBTDP1KMT2AMEN1 | |
| SCHEMBL6373320 | 0.81 | MAOA (0.34) | MAOAMAOBTDP1KMT2AMEN1 | |
| SCHEMBL13074363 | 0.80 | MAOA (0.41) | MAOAMAOBTDP1CTSKKMT2A | |
| SCHEMBL26464845 | 0.79 | DGAT1 (0.33) | MAOAMAOBTDP1CTSK | |
| SCHEMBL12074271 | 0.79 | KDM4C (0.36) | MAOAMAOBKDM4CTDP1CTSK | |
| SCHEMBL13074364 | 0.79 | MEN1 (0.40) | MAOAMAOBKDM4CCTSKKMT2A | |
| SCHEMBL3808762 | 0.78 | CRBN (0.34) | MAOAMAOBCTSK | |
| SCHEMBL3808765 | 0.78 | CRBN (0.34) | MAOAMAOBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2706062-B1 | NOVEL CEPHALOSPORIN DERIVATIVE AND PHARMACEUTICAL COMPOSITION THEREOF | LEGOCHEM BIOSCIENCES INC (KR) | 2018-05-09 | — | — | EP | disclosed |