Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 8/20 | 0.72 |
| ▸ | KDM5A | P29375 | 5/20 | 0.72 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | SPR | P35270 | 2/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16148987 | 0.83 | KDM5A (1.00) | KDM4CKDM5AKDM5B | |
| SCHEMBL16149052 | 0.81 | KDM5A (0.79) | KDM4CKDM5AKDM5BPTPN11CNR2 | |
| SCHEMBL20125334 | 0.80 | KDM4C (0.66) | KDM4CKDM5AKDM5BPTPN11HRH4 | |
| SCHEMBL20125368 | 0.79 | KDM4C (0.68) | KDM4CKDM5AKDM5BHRH4 | |
| SCHEMBL20125377 | 0.72 | KDM4C (0.73) | KDM4CKDM5AKDM5B | |
| SCHEMBL20125439 | 0.70 | KDM4C (0.75) | KDM4CKDM5AKDM5B | |
| SCHEMBL16157398 | 0.65 | KDM5A (0.74) | KDM4CKDM5AKDM5B | |
| SCHEMBL20125322 | 0.63 | KDM5A (0.62) | KDM4CKDM5AKDM5BPTPN11 | |
| SCHEMBL20125330 | 0.63 | KDM5B (0.62) | KDM4CKDM5AKDM5BPTPN11 | |
| SCHEMBL16149664 | 0.63 | KDM5A (0.57) | KDM4CKDM5AKDM5BPTPN11HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968282-B1 | HISTONE DEMENTHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2018-05-09 | — | — | EP | disclosed |