Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 7/20 | 0.62 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.49 |
| ▸ | KDM4A | O75164 | 2/20 | 0.49 |
| ▸ | KDM5B | Q9UGL1 | 7/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20125475 | 0.89 | KDM5A (0.56) | KDM5AKDM4CKDM4AKDM5B | |
| SCHEMBL20125340 | 0.89 | KDM4C (0.64) | KDM5AKDM4CKDM4AKDM5B | |
| SCHEMBL20125349 | 0.79 | KDM4C (0.58) | KDM5AKDM4CKDM4AKDM5B | |
| SCHEMBL20125360 | 0.79 | KDM4C (0.65) | KDM5AKDM4CKDM4AKDM5B | |
| SCHEMBL16149631 | 0.77 | KDM5A (1.00) | KDM5AKDM4CKDM4AKDM5B | |
| SCHEMBL16149780 | 0.75 | KDM5A (0.78) | KDM5AKDM4CKDM4AKDM5B | |
| SCHEMBL20125476 | 0.74 | KDM4C (0.70) | KDM5AKDM4CKDM4AKDM5B | |
| SCHEMBL20125357 | 0.74 | KDM5B (0.57) | KDM5AKDM4CKDM4AKDM5B | |
| SCHEMBL20125332 | 0.65 | KDM4C (0.62) | KDM5AKDM4CKDM4AKDM5B | |
| SCHEMBL16150547 | 0.65 | KDM4C (0.82) | KDM5AKDM4CKDM4AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968282-B1 | HISTONE DEMENTHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2018-05-09 | — | — | EP | disclosed |