Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | HNF4A | P41235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2999177 | 0.87 | CA2 (0.33) | HSD11B1 | |
| SCHEMBL27780028 | 0.85 | ALDH1A1 (0.37) | DPP4PDCD1CD274ALDH1A1HSD17B10 | |
| SCHEMBL3228462 | 0.77 | BACE1 (0.38) | ALDH1A1HSD17B10HPGDBCL2L1CYP2A6 | |
| SCHEMBL30734357 | 0.76 | ALDH1A1 (0.36) | ALDH1A1HSD11B1 | |
| SCHEMBL34188 | 0.73 | ALDH1A1 (0.40) | ALDH1A1MAPK1 | |
| SCHEMBL29624141 | 0.73 | ALDH1A1 (0.40) | ALDH1A1MAPK1 | |
| SCHEMBL1194487 | 0.73 | CA2 (0.41) | DPP4PDCD1CD274ALDH1A1HSD17B10 | |
| SCHEMBL27480276 | 0.73 | CA2 (0.41) | DPP4PDCD1CD274ALDH1A1HSD17B10 | |
| SCHEMBL26004347 | 0.72 | ALDH1A1 (0.42) | DPP4PDCD1CD274ALDH1A1HSD17B10 | |
| SCHEMBL545685 | 0.72 | CA2 (0.40) | DPP4PDCD1CD274ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073653-A1 | IMPROVED CARBONYLATION PROCESS | LUCITE INTERNATIONAL UK LIMITED (GB) | 2011-06-23 | — | — | WO | disclosed |