Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2013285 | 0.84 | MAPT (0.38) | MAPTPOLBTHRBALDH1A1HSP90AA1 | |
| SCHEMBL2013308 | 0.81 | MAPT (0.41) | MAPTPOLBTHRBALDH1A1HSP90AA1 | |
| SCHEMBL2013918 | 0.79 | MAPT (0.40) | MAPTPOLBTHRBALDH1A1HSP90AA1 | |
| SCHEMBL2014050 | 0.79 | MAPT (0.40) | MAPTPOLBTHRBALDH1A1HSP90AA1 | |
| SCHEMBL2015184 | 0.79 | ALDH1A1 (0.45) | MAPTPOLBALDH1A1KMT2A | |
| SCHEMBL2014705 | 0.79 | MAPT (0.43) | MAPTPOLBTHRBALDH1A1HSP90AA1 | |
| SCHEMBL16168628 | 0.78 | MAPT (0.36) | MAPTPOLBTHRBALDH1A1HSP90AA1 | |
| SCHEMBL2012033 | 0.78 | MAPT (0.36) | MAPTPOLBTHRBALDH1A1HSP90AA1 | |
| SCHEMBL2011972 | 0.77 | GAA (0.42) | MAPTPOLBALDH1A1KMT2A | |
| SCHEMBL2012998 | 0.76 | L3MBTL1 (0.43) | MAPTPOLBALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2513069-A1 | ANTIFUNGAL COMPOUNDS | Katholieke Universiteit Leuven (BE) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011072345-A1 | ANTIFUNGAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2011-06-23 | — | — | WO | disclosed |