Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.51 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.50 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17854025 | 0.83 | NPC1 (0.51) | NPC1MAPTRAB9AADRB2ADRB1 | |
| SCHEMBL9943601 | 0.83 | PARP15 (0.55) | ADRB2ADRB1ADRB3PARP15PARP10 | |
| SCHEMBL19892096 | 0.83 | ADRB2 (0.59) | NPC1MAPTRAB9AADRB2ADRB1 | |
| SCHEMBL20664967 | 0.80 | NPC1 (0.48) | NPC1MAPTRAB9AADRB2ADRB1 | |
| SCHEMBL9288915 | 0.79 | ADRB2 (0.55) | NPC1MAPTRAB9AADRB2ADRB1 | |
| SCHEMBL1515794 | 0.79 | MAPT (0.59) | NPC1MAPTRAB9AADRB2ADRB1 | |
| SCHEMBL218978 | 0.79 | DRD2 (0.45) | PARP15PARP10PARP2POLBCHRNB2 | |
| SCHEMBL16425305 | 0.79 | DRD2 (0.45) | PARP15PARP10PARP2CHRNB2CHRNA4 | |
| SCHEMBL10932224 | 0.78 | PARP10 (0.70) | MAPTPARP15PARP10PARP2SMN1; SMN2 | |
| SCHEMBL27648416 | 0.77 | PARP15 (0.45) | NPC1MAPTRAB9AADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180127537-A1 | RESINS AND COMPOSITIONS FOR HIGH TEMPERATURE APPLICATIONS | HENKEL AG & CO. KGAA (DE) | 2018-05-10 | — | — | US | disclosed |