SCHEMBL20126469

SCHEMBL20126469

CCOc1ccc2cc(B(O)O)sc2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 5/20 0.50
ALDH1A1 P00352 4/20 0.50
TP53 P04637 3/20 0.50
CYP3A4 P08684 2/20 0.50
TSHR P16473 1/20 0.50
MGLL Q99685 1/20 0.49
KMT2A Q03164 4/20 0.47
MAPT P10636 4/20 0.44
PSMB8 P28062 1/20 0.44
SMN1; SMN2 Q16637 5/20 0.43
NPC1 O15118 4/20 0.43
RAB9A P51151 4/20 0.43
TDP1 Q9NUW8 2/20 0.43
MEN1 O00255 2/20 0.43
HPGD P15428 2/20 0.43
NFKB1 P19838 2/20 0.43
NFKB2 Q00653 2/20 0.43
RELA Q04206 2/20 0.43
NPSR1 Q6W5P4 1/20 0.43
APOBEC3G Q9HC16 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3057905 0.82 MGLL (0.44) HSD17B10ALDH1A1TP53CYP3A4TSHR
SCHEMBL225978 0.82 MGLL (0.53) ALDH1A1CYP3A4MGLLKMT2AMAPT
SCHEMBL29953220 0.82 MGLL (0.53) ALDH1A1CYP3A4MGLLKMT2AMAPT
SCHEMBL3059085 0.82 MGLL (0.46) MGLLMAPTCA12CA1CA2
SCHEMBL3053613 0.81 MGLL (0.45) MGLLMAPTCA12CA1CA2
SCHEMBL6605446 0.78 MGLL (0.49) ALDH1A1MGLLKMT2ACA2POLB
SCHEMBL29958250 0.78 MGLL (0.49) ALDH1A1MGLLKMT2ACA2POLB
SCHEMBL13885724 0.77 ALDH1A1 (0.51) HSD17B10ALDH1A1TP53CYP3A4TSHR
SCHEMBL3049639 0.76 MGLL (0.38) HSD17B10ALDH1A1TP53CYP3A4TSHR
SCHEMBL5534564 0.76 ALDH1A1 (0.50) HSD17B10ALDH1A1TP53CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180127652-A1 LIQUID CRYSTAL COMPOUND HAVING BENZOTHIOPHENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-05-10 US disclosed