SCHEMBL20127422

SCHEMBL20127422

c1ccc2c(c1)oc1c(-c3ccc(-c4c5ccccc5c(-c5cc6c7ccccc7oc6c6ccccc56)c5ccccc45)cc3)cccc12

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.57
GGPS1 O95749 1/20 0.43
PRKDC P78527 6/20 0.42
PTGES2 Q9H7Z7 1/20 0.40
AHR P35869 1/20 0.40
ATM Q13315 1/20 0.38
DYRK1A Q13627 1/20 0.37
PIK3CD O00329 1/20 0.36
PIK3CB P42338 1/20 0.36
PRMT5 O14744 1/20 0.35
WDR77 Q9BQA1 1/20 0.35
HDAC8 Q9BY41 1/20 0.34
CDC14B O60729 2/20 0.33
CDC14A Q9UNH5 2/20 0.33
PLA2G2A P14555 1/20 0.33
PLA2G4A P47712 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL125801 0.91 ALOX5 (0.62) ALOX5GGPS1PRKDCPTGES2AHR
SCHEMBL12011474 0.90 ALOX5 (0.53) ALOX5GGPS1PRKDCPTGES2AHR
SCHEMBL10122455 0.90 ALOX5 (0.47) ALOX5GGPS1PRKDCAHRATM
SCHEMBL20127430 0.90 ALOX5 (0.56) ALOX5GGPS1PRKDCPTGES2AHR
SCHEMBL20127414 0.89 ALOX5 (0.54) ALOX5GGPS1PRKDCPTGES2AHR
SCHEMBL20127694 0.89 ALOX5 (0.52) ALOX5GGPS1PRKDCPTGES2AHR
SCHEMBL27046491 0.89 ALOX5 (0.52) ALOX5GGPS1PRKDCPTGES2ATM
SCHEMBL20127661 0.88 ALOX5 (0.57) ALOX5GGPS1PRKDCPTGES2AHR
SCHEMBL10122460 0.88 ALOX5 (0.46) ALOX5GGPS1AHRDYRK1APLA2G2A
SCHEMBL125788 0.88 ALOX5 (0.56) ALOX5GGPS1PRKDCPTGES2AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE RER1, NR0B1, NR2E1 ALOX5 4115/4885GGPS1 4058/4885PRKDC 3891/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.