SCHEMBL20127426

SCHEMBL20127426

CC1(C)c2ccccc2-c2ccc(-c3cccc(-c4c5ccccc5c(-c5cc6c7ccccc7oc6c6ccccc56)c5ccccc45)c3)cc21

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.39
PRKDC P78527 1/20 0.33
PDK2 Q15119 4/20 0.33
PLA2G2A P14555 2/20 0.33
PLA2G4A P47712 2/20 0.33
GGPS1 O95749 1/20 0.33
PGR P06401 2/20 0.32
MEN1 O00255 1/20 0.32
CYP2C19 P33261 1/20 0.32
KMT2A Q03164 1/20 0.32
PLA2G10 O15496 1/20 0.31
PTGES2 Q9H7Z7 1/20 0.31
AHR P35869 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17944562 0.96 ALOX5 (0.40) ALOX5PRKDCGGPS1PGRMEN1
SCHEMBL20127419 0.93 ALOX5 (0.38) ALOX5PRKDCPDK2PGRMEN1
SCHEMBL20127695 0.91 ALOX5 (0.35) ALOX5PDK2PLA2G2APLA2G4AMEN1
SCHEMBL20127657 0.90 ALOX5 (0.38) ALOX5PRKDCPDK2PLA2G2APLA2G4A
SCHEMBL18272692 0.90 ALOX5 (0.50) ALOX5PRKDCPDK2PLA2G2APLA2G4A
SCHEMBL20127630 0.89 ALOX5 (0.39) ALOX5PRKDCPDK2PLA2G2APLA2G4A
SCHEMBL19109883 0.88 ALOX5 (0.36) ALOX5PRKDCPGRAHR
SCHEMBL13488111 0.88 ALOX5 (0.43) ALOX5PRKDCPDK2GGPS1PGR
SCHEMBL13487888 0.87 ALOX5 (0.40) ALOX5PRKDCPDK2PLA2G2APLA2G4A
SCHEMBL19109527 0.87 ALOX5 (0.38) ALOX5PRKDCGGPS1PGRPTGES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE RER1, NR0B1, NR2E1 ALOX5 4115/4885PRKDC 3891/4885PDK2 2781/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.