Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GYS1 | P13807 | 6/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | AGXT | P21549 | 1/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2013211 | 0.92 | GYS1 (0.38) | GYS1FFAR1MRGPRX4MAPTMAOB | |
| SCHEMBL2012937 | 0.89 | MGAM (0.45) | GYS1FFAR1MRGPRX4MAOB | |
| SCHEMBL2012370 | 0.74 | GYS1 (0.52) | GYS1MAOBGSTP1 | |
| SCHEMBL12585463 | 0.72 | GSTP1 (0.54) | FFAR1MRGPRX4MAPTMAOAMAOB | |
| SCHEMBL2012748 | 0.71 | PTGER1 (0.48) | GYS1MRGPRX4MAPTKDM1AMAOB | |
| SCHEMBL2012405 | 0.71 | GYS1 (0.54) | GYS1MAOBGSTP1 | |
| SCHEMBL2011729 | 0.71 | GYS1 (0.54) | GYS1MAOB | |
| SCHEMBL1775149 | 0.71 | MAOB (0.58) | FFAR1MAPTMAOAMAOBSLC6A2 | |
| SCHEMBL18495757 | 0.70 | MGAM (0.39) | FFAR1KDM1AMAOAMAOBFFAR4 | |
| SCHEMBL2029459 | 0.69 | MAOB (0.49) | GYS1FFAR1MAOAMAOBGSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011067266-A1 | CARBOXYLIC ACID ANALOGS AS GLYCOGEN SYNTHASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-06-09 | — | — | WO | disclosed |