Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | SI | P14410 | 4/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.45 |
| ▸ | GYS1 | P13807 | 9/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2012745 | 0.89 | GYS1 (0.39) | GYS1MRGPRX4MAOBFFAR1 | |
| SCHEMBL2013211 | 0.87 | GYS1 (0.38) | GYS1MRGPRX4MAOBFFAR1PPARD | |
| SCHEMBL18495757 | 0.73 | MGAM (0.39) | MGAMGAASIMGAM2MAOB | |
| SCHEMBL2010257 | 0.72 | GYS1 (0.68) | GYS1 | |
| SCHEMBL29098923 | 0.71 | PDE4B (0.47) | — | |
| SCHEMBL29546745 | 0.71 | PDE4B (0.47) | — | |
| SCHEMBL19488935 | 0.71 | PDE4B (0.47) | MGAMGAASIMGAM2 | |
| SCHEMBL2012939 | 0.71 | GYS1 (0.48) | GYS1MRGPRX4MAOB | |
| SCHEMBL31053413 | 0.70 | ALOX5AP (0.38) | FFAR1 | |
| SCHEMBL2012370 | 0.69 | GYS1 (0.52) | GYS1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011067266-A1 | CARBOXYLIC ACID ANALOGS AS GLYCOGEN SYNTHASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-06-09 | — | — | WO | disclosed |