SCHEMBL20127554

SCHEMBL20127554

CC1(C)c2ccccc2-c2ccc(-c3c4ccccc4c(-c4ccc5c(c4)oc4cc6ccccc6cc45)c4ccccc34)cc21

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.32
HCRTR1 O43613 1/20 0.32
MAOA P21397 1/20 0.31
AHR P35869 2/20 0.30
PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10122705 0.97 HCRTR1 (0.32) PGRHCRTR1PDK2
SCHEMBL20127557 0.97 PDK2 (0.33) PGRHCRTR1PDK2
SCHEMBL20127566 0.96 PDK2 (0.33) PGRHCRTR1PDK2
SCHEMBL17944239 0.93 HSP90AA1 (0.33) PGRMAOAAHRPDK2
SCHEMBL17944712 0.93 PGR (0.32) PGRHCRTR1AHR
SCHEMBL17944569 0.92 ESR1 (0.35) PGRHCRTR1
SCHEMBL17944119 0.91 PSD (0.33) PGRMAOA
SCHEMBL24130691 0.90 AHR (0.39) PGRHCRTR1MAOAAHR
SCHEMBL16068026 0.90 PDK2 (0.33) PGRHCRTR1PDK2
SCHEMBL19109872 0.89 HSP90AA1 (0.37) PGRHCRTR1MAOAAHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE RER1, NR0B1, NR2E1 PGR 1148/4885HCRTR1 1635/4885MAOA 312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.