Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | PTAFR | P25105 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17246877 | 0.94 | MAPK1 (0.47) | MAPK1HTTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL21392584 | 0.92 | MAPK1 (0.50) | MAPK1HTTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL22218980 | 0.91 | MAPK1 (0.46) | MAPK1HTTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL20127747 | 0.89 | PDE10A (0.39) | MAPK1HTTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL20127749 | 0.88 | ESR1 (0.49) | MAPK1HTTALDH1A1KDM4EESR1 | |
| SCHEMBL21392595 | 0.88 | MAPK1 (0.50) | MAPK1HTTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL21392677 | 0.88 | MAPK1 (0.45) | MAPK1HTTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL20127751 | 0.87 | ESR1 (0.44) | MAPK1HTTALDH1A1ESR1ESR2 | |
| SCHEMBL26345591 | 0.85 | MAPK1 (0.47) | MAPK1HTTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL22217560 | 0.84 | MAPK1 (0.46) | MAPK1HTTALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180130968-A1 | ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2018-05-10 | — | — | US | disclosed |
| US-20180130968-A1 | ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180130968-A1 | ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE | RER1, NR0B1, NR2E1 | MAPK1 1035/4885HTT 4764/4885ALDH1A1 476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.