Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 10/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17246878 | 0.94 | PDE10A (0.39) | PDE10ACYP1A2ALDH1A1KDM4EMEN1 | |
| SCHEMBL21392653 | 0.93 | RECQL (0.41) | PDE10ACYP1A2ALDH1A1KDM4EMEN1 | |
| SCHEMBL21392592 | 0.89 | PDE10A (0.41) | PDE10ACYP1A2ALDH1A1KDM4EMEN1 | |
| SCHEMBL20127752 | 0.89 | MAPK1 (0.47) | PDE10ACYP1A2ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL21392433 | 0.88 | PDE10A (0.38) | PDE10ACYP1A2ALDH1A1KDM4EMEN1 | |
| SCHEMBL26345601 | 0.88 | PDE10A (0.40) | PDE10ACYP1A2ALDH1A1KDM4EMEN1 | |
| SCHEMBL20127749 | 0.86 | ESR1 (0.49) | ALDH1A1KDM4EMEN1MAPTHPGD | |
| SCHEMBL26345599 | 0.85 | PDE10A (0.39) | PDE10ACYP1A2ALDH1A1KDM4EMEN1 | |
| SCHEMBL26345483 | 0.85 | PDE10A (0.39) | PDE10ACYP1A2ALDH1A1KDM4EMEN1 | |
| SCHEMBL22217326 | 0.85 | ALDH1A1 (0.37) | PDE10ACYP1A2ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180130968-A1 | ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2018-05-10 | — | — | US | disclosed |
| US-20180130968-A1 | ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180130968-A1 | ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE | RER1, NR0B1, NR2E1 | PDE10A 3617/4885CYP1A2 821/4885ALDH1A1 476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.