SCHEMBL20127774

SCHEMBL20127774

CC1(C)c2ccccc2-c2ccc(N(c3ccc(-c4cccc5c4sc4ccccc45)cc3)c3ccc4c(c3)-c3ccccc3C4(c3ccccc3)c3ccccc3)cc21

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.39
PRKDC P78527 1/20 0.32
PARP14 Q460N5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17855578 0.97 ALOX5 (0.40) ALOX5PRKDCPARP14
SCHEMBL18468723 0.97 ALOX5 (0.41) ALOX5PRKDCPARP14
SCHEMBL18468900 0.96 ALOX5 (0.38) ALOX5PRKDCPARP14
SCHEMBL16996182 0.96 ALOX5 (0.40) ALOX5PRKDCPARP14
SCHEMBL17804856 0.96 ALOX5 (0.40) ALOX5PRKDCPARP14
SCHEMBL20127794 0.95 ALOX5 (0.37) ALOX5PRKDC
SCHEMBL20127813 0.95 ALOX5 (0.37) ALOX5PRKDC
SCHEMBL17816922 0.95 ALOX5 (0.39) ALOX5PRKDCPARP14
SCHEMBL9916369 0.95 ALOX5 (0.39) ALOX5PRKDCPARP14
SCHEMBL24905021 0.94 ALOX5 (0.41) ALOX5PRKDCPARP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3127894-B1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO (JP) 2021-04-28 EP disclosed
US-10854822-B2 Compound, material for organic electroluminescent element, organic electroluminescent element, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2020-12-01 US disclosed
US-20180190904-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2018-07-05 US disclosed
US-20180190904-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2018-07-05 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE RER1, NR0B1, NR2E1 ALOX5 4115/4885PRKDC 3891/4885PARP14 4175/4885
US-20180190904-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE ESR1, L1CAM, ELAVL1 ALOX5 579/4885PRKDC 4860/4885PARP14 1790/4885
US-10854822-B2 Compound, material for organic electroluminescent element, organic electroluminescent element, and electronic device ESR1, L1CAM, ELAVL1 ALOX5 579/4885PRKDC 4860/4885PARP14 1790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.