Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10455979 | 0.86 | MAPT (0.50) | NPC1RAB9AMAPTPOLBCYP2C9 | |
| SCHEMBL23323195 | 0.85 | NPC1 (0.44) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL5874076 | 0.82 | RAB9A (0.63) | NPC1RAB9AMAPTPOLBLMNA | |
| SCHEMBL28774723 | 0.81 | NPC1 (0.50) | NPC1RAB9AMAPTPOLBCYP2C9 | |
| SCHEMBL22118677 | 0.80 | NPC1 (0.47) | NPC1RAB9AMAPTPOLBLMNA | |
| SCHEMBL444583 | 0.80 | MEN1 (0.59) | NPC1RAB9APOLBCYP2C9ALDH1A1 | |
| SCHEMBL3435838 | 0.80 | EPHX2 (0.49) | NPC1RAB9AMAPTPOLBCYP2C9 | |
| SCHEMBL18535911 | 0.78 | NPC1 (0.45) | NPC1RAB9AMAPTPOLBCYP2C9 | |
| SCHEMBL9483965 | 0.78 | EPHX2 (0.50) | NPC1RAB9AMAPTPOLBCYP2C9 | |
| SCHEMBL11615735 | 0.78 | NPC1 (0.45) | NPC1RAB9AMAPTPOLBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180127606-A1 | ENERGY CURABLE INKJET INKS AND COATING COMPOSITIONS | SUN CHEMICAL CORPORATION (US) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180127606-A1 | ENERGY CURABLE INKJET INKS AND COATING COMPOSITIONS | PNMT, PHOSPHO1, KMT5A | NPC1 3894/4885RAB9A 1838/4885MAPT 499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.