SCHEMBL20128392

SCHEMBL20128392

COC(=O)CCN(C)C(C)=O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.61
MEN1 O00255 1/20 0.61
TSHR P16473 4/20 0.52
MGAM O43451 1/20 0.42
GAA P10253 1/20 0.42
SI P14410 1/20 0.42
MGAM2 Q2M2H8 1/20 0.42
KDM5A P29375 2/20 0.41
LMNA P02545 3/20 0.39
CA12 O43570 1/20 0.39
CA14 Q9ULX7 1/20 0.39
KDM4E B2RXH2 1/20 0.39
HSD17B10 Q99714 2/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPT P10636 1/20 0.38
HTT P42858 1/20 0.38
KDM6B O15054 1/20 0.35
KDM5C P41229 1/20 0.35
EGLN1 Q9GZT9 1/20 0.35
PHF8 Q9UPP1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28721469 0.82 KMT2A (0.61) KMT2AMEN1TSHRMGAMGAA
SCHEMBL16494983 0.80 KMT2A (0.59) KMT2AMEN1TSHRMGAMGAA
SCHEMBL7670649 0.78 CA12 (0.46) KMT2AMEN1TSHRMGAMGAA
SCHEMBL5788270 0.78 KMT2A (0.95) KMT2AMEN1TSHRMGAMGAA
SCHEMBL215293 0.78
SCHEMBL440142 0.78 PHF8 (0.44) KDM5ALMNAKDM4EKDM6BKDM5C
SCHEMBL4097713 0.77 KMT2A (0.55) KMT2AMEN1TSHRMGAMGAA
SCHEMBL948960 0.77 MEN1 (0.36) KMT2AMEN1CA12CA14KDM6B
SCHEMBL29118277 0.77 KMT2A (0.55) KMT2AMEN1TSHRMGAMGAA
SCHEMBL5788763 0.77 KMT2A (0.50) KMT2AMEN1TSHRMGAMGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10781325-B2 Curable composition, curable ink, accommodating container, image forming device, image forming method, cured matter, and acrylamide compound RICOH COMPANY, LTD. (JP) 2020-09-22 US disclosed
US-20180127607-A1 CURABLE COMPOSITION, CURABLE INK, ACCOMMODATING CONTAINER, IMAGE FORMING DEVICE, IMAGE FORMING METHOD, CURED MATTER, AND ACRYLAMIDE COMPOUND RICOH COMPANY, LTD. (JP) 2018-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10781325-B2 Curable composition, curable ink, accommodating container, image forming device, image forming method, cured matter, and acrylamide compound CRYAA, CDKN1A, ACR KMT2A 1996/4885MEN1 386/4885TSHR 4587/4885
US-20180127607-A1 CURABLE COMPOSITION, CURABLE INK, ACCOMMODATING CONTAINER, IMAGE FORMING DEVICE, IMAGE FORMING METHOD, CURED MATTER, AND ACRYLAMIDE COMPOUND CRYAA, CDKN1A, ACR KMT2A 1996/4885MEN1 386/4885TSHR 4587/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.