Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 5/20 | 0.42 |
| ▸ | CA9 | Q16790 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18615416 | 0.90 | MAPT (0.48) | MAPTNPC1RAB9ACA12CA1 | |
| SCHEMBL15869171 | 0.84 | NPC1 (0.43) | MAPTNPC1RAB9ACA12CA1 | |
| SCHEMBL15869165 | 0.84 | NPC1 (0.43) | MAPTNPC1RAB9ACA12CA1 | |
| SCHEMBL19901773 | 0.83 | ALDH1A1 (0.42) | MAPTNPC1RAB9ACA12CA1 | |
| SCHEMBL15869173 | 0.77 | NPC1 (0.38) | MAPTNPC1RAB9AALDH1A1KDM4E | |
| 1,4-Diallyloxybenzene SCHEMBL302448 | 0.75 | CA12 (0.63) | MAPTNPC1RAB9ACA12CA1 | |
| SCHEMBL3026306 | 0.75 | MAPT (0.46) | MAPTNPC1RAB9ACA12CA1 | |
| SCHEMBL9187651 | 0.74 | ALDH1A1 (0.37) | NPC1RAB9AALDH1A1KDM4ELMNA | |
| SCHEMBL12354906 | 0.72 | CA12 (0.45) | MAPTNPC1RAB9ACA12CA1 | |
| SCHEMBL11658554 | 0.72 | TDP1 (0.59) | MAPTNPC1RAB9ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180127537-A1 | RESINS AND COMPOSITIONS FOR HIGH TEMPERATURE APPLICATIONS | HENKEL AG & CO. KGAA (DE) | 2018-05-10 | — | — | US | disclosed |