SCHEMBL20129504

SCHEMBL20129504

CC1(C)c2ccccc2-c2cc3c4cc(-c5ccc6c(c5)c5cc7c8ccccc8n(-c8ccccc8)c7cc5n6-c5ccccc5)ccc4n(-c4cccc(-c5ccccc5)c4)c3cc21

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TSPO P30536 2/20 0.34
HDAC4 P56524 1/20 0.32
PTGER4 P35408 1/20 0.31
PDE10A Q9Y233 1/20 0.31
PGR P06401 1/20 0.30
PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14822517 0.98 L3MBTL1 (0.39) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL10001475 0.98 L3MBTL1 (0.39) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL16283009 0.98 L3MBTL1 (0.39) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL19653626 0.97 KDM4E (0.38) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL18254314 0.97 KDM4E (0.38) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL17760011 0.97 KDM4E (0.38) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL15137658 0.97 L3MBTL1 (0.40) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL14822512 0.97 KDM4E (0.37) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL15946301 0.96 KDM4E (0.38) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL18062352 0.95 KDM4E (0.37) KDM4EATML3MBTL1TSPOPTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10651396-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same LG DISPLAY CO., LTD. (KR) 2020-05-12 US disclosed
US-20180130953-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2018-05-10 US disclosed
US-20180130953-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2018-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10651396-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same AOX1, OCIAD1, OCIAD2 KDM4E 2238/4885ATM 3082/4885L3MBTL1 155/4885
US-20180130953-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME AOX1, OCIAD1, OCIAD2 KDM4E 2238/4885ATM 3082/4885L3MBTL1 155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.