Sugi Predict

Sugi Predict / Compounds / SCHEMBL20129513

SCHEMBL20129513

SCHEMBL20129513

c1ccc(-c2ccc3c(c2)c2cc4c(cc2n3-c2ccc(-c3nc(-c5ccccc5)nc(-c5ccccc5)n3)cc2)oc2ccccc24)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PLA2G2A P14555 4/20 0.36
▸ PLA2G4A P47712 4/20 0.36
▸ AHR P35869 2/20 0.35
▸ CHEK2 O96017 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ PTGER4 P35408 1/20 0.33
▸ MMP12 P39900 1/20 0.33
▸ MMP13 P45452 1/20 0.33
▸ NR3C1 P04150 1/20 0.33
▸ PLA2G10 O15496 1/20 0.33
▸ MAOA P21397 1/20 0.33
▸ KDM4E B2RXH2 2/20 0.33
▸ L3MBTL1 Q9Y468 2/20 0.33
▸ ATM Q13315 1/20 0.33
▸ PGR P06401 1/20 0.32
▸ MAPT P10636 2/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ NPC1 O15118 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19830594 0.98 KDM4E (0.36) PLA2G2APLA2G4AAHRCHEK2TSHR
SCHEMBL19830501 0.94 KDM4E (0.39) PLA2G2APLA2G4AAHRCHEK2TSHR
SCHEMBL19830784 0.94 KDM4E (0.39) PLA2G2APLA2G4AAHRCHEK2TSHR
SCHEMBL18505403 0.94 KDM4E (0.40) PLA2G2APLA2G4AAHRCHEK2TSHR
SCHEMBL23595251 0.94 KDM4E (0.40) PLA2G2APLA2G4AAHRCHEK2TSHR
SCHEMBL19830342 0.93 KDM4E (0.34) PLA2G2APLA2G4AAHRCHEK2TSHR
SCHEMBL19830620 0.93 KDM4E (0.34) PLA2G2APLA2G4AAHRCHEK2TSHR
SCHEMBL20129511 0.93 PLA2G2A (0.35) PLA2G2APLA2G4AAHRCHEK2TSHR
SCHEMBL24217118 0.93 KDM4E (0.37) PLA2G2APLA2G4AAHRCHEK2TSHR
SCHEMBL25660298 0.93 KDM4E (0.37) PLA2G2APLA2G4AAHRCHEK2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10651396-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same LG DISPLAY CO., LTD. (KR) 2020-05-12 — — US disclosed
US-20180130953-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2018-05-10 — — US disclosed
US-20180130953-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2018-05-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10651396-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same AOX1, OCIAD1, OCIAD2 PLA2G2A 4571/4885PLA2G4A 4122/4885AHR 1401/4885
US-20180130953-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME AOX1, OCIAD1, OCIAD2 PLA2G2A 4571/4885PLA2G4A 4122/4885AHR 1401/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.