Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 3/20 | 0.60 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | MERTK | Q12866 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.41 |
| ▸ | STK17A | Q9UEE5 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | STK17B | O94768 | 3/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20129533 | 0.94 | FLT3 (0.59) | FLT3SYKAURKAMERTKABCB1 | |
| SCHEMBL20172044 | 0.94 | FLT3 (0.54) | FLT3SYKAURKAMERTKABCB1 | |
| SCHEMBL15585199 | 0.93 | FLT3 (0.58) | FLT3SYKSTK17ASTK17BCHEK1 | |
| SCHEMBL15584131 | 0.93 | FLT3 (0.60) | FLT3SYKAURKAMERTKABCB1 | |
| Hydrochloric Acid SCHEMBL21046222 | 0.92 | FLT3 (0.57) | FLT3SYKSTK17ASTK17BCHEK1 | |
| SCHEMBL15584311 | 0.88 | FLT3 (0.53) | FLT3SYKAURKAMERTKABCB1 | |
| SCHEMBL15584132 | 0.88 | FLT3 (0.57) | FLT3SYKAURKAMERTKABCB1 | |
| SCHEMBL15585828 | 0.87 | FLT3 (0.65) | FLT3SYKAURKAMERTKGRM5 | |
| SCHEMBL16450120 | 0.87 | FLT3 (0.65) | FLT3SYKAURKAMERTKSTK17A | |
| SCHEMBL16450152 | 0.86 | FLT3 (0.55) | FLT3SYKAURKAMERTKABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180127382-A1 | METHOD FOR MANUFACTURING NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND INTERMEDIATE OF SAME | FUJIFILM CORPORATION (JP) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180127382-A1 | METHOD FOR MANUFACTURING NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND INTERMEDIATE OF SAME | FLT3, ARG1, KIT | FLT3 1/4885SYK 54/4885AURKA 568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.