Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 3/20 | 0.54 |
| ▸ | SYK | P43405 | 2/20 | 0.49 |
| ▸ | AURKA | O14965 | 3/20 | 0.44 |
| ▸ | PGK1 | P00558 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 2/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 3/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20129536 | 0.94 | FLT3 (0.60) | FLT3SYKAURKACYP1A2CYP2D6 | |
| SCHEMBL20129533 | 0.88 | FLT3 (0.59) | FLT3SYKAURKACYP1A2CYP2D6 | |
| SCHEMBL15585199 | 0.87 | FLT3 (0.58) | FLT3SYK | |
| SCHEMBL15584131 | 0.87 | FLT3 (0.60) | FLT3SYKAURKAPGK1CYP1A2 | |
| Hydrochloric Acid SCHEMBL21046222 | 0.86 | FLT3 (0.57) | FLT3SYK | |
| SCHEMBL20172039 | 0.82 | FLT3 (0.56) | FLT3SYKAURKAPGK1CYP1A2 | |
| SCHEMBL15584744 | 0.82 | FLT3 (0.63) | FLT3SYKAURKAGRM5JAK3 | |
| SCHEMBL15584132 | 0.82 | FLT3 (0.57) | FLT3SYKAURKACYP1A2CYP2D6 | |
| SCHEMBL19676120 | 0.82 | FLT3 (0.49) | FLT3SYKAURKACYP1A2CYP2D6 | |
| SCHEMBL15584311 | 0.82 | FLT3 (0.53) | FLT3SYKAURKACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3323811-A1 | PRODUCTION METHOD FOR NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, AND INTERMEDIATE OF SAID NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | FUJIFILM Corporation (JP) | 2018-05-23 | — | — | EP | disclosed |