Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.57 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | PADI4 | Q9UM07 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2013001 | 0.89 | HCRTR1 (0.56) | HCRTR1HCRTR2NPC1RAB9AOPRM1 | |
| SCHEMBL2015686 | 0.87 | HCRTR1 (0.55) | HCRTR1HCRTR2NPC1RAB9AOPRM1 | |
| SCHEMBL2014124 | 0.87 | HCRTR1 (0.59) | HCRTR1HCRTR2NPC1RAB9APADI4 | |
| SCHEMBL2014646 | 0.86 | HCRTR1 (0.56) | HCRTR1HCRTR2NPC1RAB9A | |
| SCHEMBL2011001 | 0.83 | HCRTR1 (0.59) | HCRTR1HCRTR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2013021 | 0.82 | HCRTR1 (0.57) | HCRTR1HCRTR2NPC1RAB9APADI4 | |
| SCHEMBL2054212 | 0.81 | HCRTR1 (0.60) | HCRTR1HCRTR2NPC1RAB9APADI4 | |
| SCHEMBL2054210 | 0.81 | HCRTR1 (0.60) | HCRTR1HCRTR2NPC1RAB9APADI4 | |
| SCHEMBL13139060 | 0.81 | HCRTR1 (0.77) | HCRTR1HCRTR2NPC1RAB9APADI4 | |
| SCHEMBL2011910 | 0.81 | HCRTR1 (0.69) | HCRTR1HCRTR2NPC1RAB9AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073316-A1 | 4-ARYL-BUTANE-1,3-DIAMIDES | NOVARTIS AG (CH) | 2011-06-23 | — | — | WO | disclosed |