Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CNR2 | P34972 | 5/20 | 0.47 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.43 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20126898 | 0.89 | KMT2A (0.50) | ALDH1A1HPGDMAPTKMT2ACNR2 | |
| SCHEMBL20099708 | 0.88 | KMT2A (0.50) | ALDH1A1HPGDMAPTKMT2ACNR2 | |
| SCHEMBL26309847 | 0.86 | CNR2 (0.50) | ALDH1A1HPGDMAPTKMT2ACNR2 | |
| SCHEMBL20130665 | 0.84 | KMT2A (0.47) | ALDH1A1HPGDMAPTKMT2ACNR2 | |
| SCHEMBL4923932 | 0.78 | ALDH1A1 (0.60) | ALDH1A1HPGDMAPTKMT2AMMP2 | |
| SCHEMBL4923938 | 0.78 | ALDH1A1 (0.60) | ALDH1A1HPGDMAPTKMT2AMMP2 | |
| SCHEMBL6136364 | 0.77 | CNR2 (0.58) | ALDH1A1KMT2ACNR2PSMB8PSMB5 | |
| SCHEMBL12835529 | 0.77 | CNR2 (0.61) | ALDH1A1HPGDMAPTKMT2ACNR2 | |
| SCHEMBL4916489 | 0.76 | ALDH1A1 (0.57) | ALDH1A1HPGDMAPTKMT2ALMNA | |
| SCHEMBL8380872 | 0.74 | CNR2 (0.58) | KMT2ACNR2PSMB8PSMB5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10968264-B2 | Cyclic peptide tyrosine tyrosine compounds as modulators of neuropeptide Y receptors | JANSSEN PHARMACEUTICA NV (BE) | 2021-04-06 | — | — | US | disclosed |
| US-20180127476-A1 | CYCLIC PEPTIDE TYROSINE TYROSINE COMPOUNDS AS MODULATORS OF NEUROPEPTIDE Y RECEPTORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180127476-A1 | CYCLIC PEPTIDE TYROSINE TYROSINE COMPOUNDS AS MODULATORS OF NEUROPEPTIDE Y RECEPTORS | NPY4R, NPY5R, NPY1R | ALDH1A1 4881/4885HPGD 4490/4885MAPT 4141/4885 |
| US-10968264-B2 | Cyclic peptide tyrosine tyrosine compounds as modulators of neuropeptide Y receptors | NPY4R, NPY5R, NPY1R | ALDH1A1 4881/4885HPGD 4490/4885MAPT 4141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.