Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18885276 | 0.95 | CNR2 (0.67) | CNR2ALDH1A1GAAHTTKMT2A | |
| SCHEMBL29354330 | 0.86 | ALDH1A1 (0.67) | CNR2ALDH1A1MAPTHPGDGAA | |
| SCHEMBL20099754 | 0.81 | CNR2 (0.51) | CNR2ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL12809523 | 0.81 | POLB (0.61) | CNR2ALDH1A1HTTKMT2APOLB | |
| SCHEMBL23553286 | 0.81 | CNR2 (0.66) | CNR2ALDH1A1MAPTHPGDHTT | |
| SCHEMBL19523045 | 0.80 | CNR2 (0.61) | CNR2ALDH1A1KMT2APOLBPSMB8 | |
| SCHEMBL6136328 | 0.80 | CNR2 (0.61) | CNR2ALDH1A1KMT2APOLBPSMB8 | |
| SCHEMBL6136330 | 0.80 | CNR2 (0.61) | CNR2ALDH1A1KMT2APOLBPSMB8 | |
| SCHEMBL26309847 | 0.80 | CNR2 (0.50) | CNR2ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL10929986 | 0.80 | CNR2 (0.53) | CNR2ALDH1A1GAAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298790-A1 | Daptomycin analogs as antibacterial agents | Cubist Pharmaceuticals, Inc. (US) | 2011-03-23 | — | — | EP | disclosed |