Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19287040 | 0.94 | ALDH1A1 (0.59) | ALDH1A1TDP1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL15722882 | 0.84 | TSHR (0.65) | ALDH1A1TDP1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL11983797 | 0.83 | TSHR (0.67) | ALDH1A1TDP1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL16716009 | 0.83 | TSHR (0.67) | ALDH1A1TDP1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL18844655 | 0.81 | ALDH1A1 (0.69) | ALDH1A1TDP1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL29116842 | 0.80 | ALDH1A1 (0.54) | ALDH1A1TDP1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL7144359 | 0.79 | ALDH1A1 (0.57) | ALDH1A1TDP1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL7146631 | 0.79 | ALDH1A1 (0.57) | ALDH1A1TDP1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL7135745 | 0.79 | ALDH1A1 (0.57) | ALDH1A1TDP1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL7135578 | 0.79 | ALDH1A1 (0.57) | ALDH1A1TDP1TSHRMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10610598-B2 | Linear polyester and semi-linear glycidol polymer systems: formulation and synthesis of novel monomers and macromolecular structures | VANDERBILT UNIVERSITY (US) | 2020-04-07 | — | — | US | disclosed |
| US-20180125983-A1 | Linear Polyester and Semi-Linear Glycidol Polymer Systems: Formulation and Synthesis of Novel Monomers and Macromolecular Structures | UNIV VANDERBILT (US) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180125983-A1 | Linear Polyester and Semi-Linear Glycidol Polymer Systems: Formulation and Synthesis of Novel Monomers and Macromolecular Structures | STT3A, STT3B, B3GAT3 | ALDH1A1 4091/4885TDP1 3944/4885TSHR 2588/4885 |
| US-10610598-B2 | Linear polyester and semi-linear glycidol polymer systems: formulation and synthesis of novel monomers and macromolecular structures | STT3A, STT3B, B3GAT3 | ALDH1A1 4091/4885TDP1 3944/4885TSHR 2588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.