SCHEMBL20130940

SCHEMBL20130940

CCCCCC(CCC)SSc1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ CSNK1E P49674 1/20 0.40
▸ MAPT P10636 1/20 0.37
▸ HPGD P15428 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ MGLL Q99685 1/20 0.37
▸ HSD17B10 Q99714 1/20 0.37
▸ CNR2 P34972 1/20 0.36
▸ LMNA P02545 1/20 0.33
▸ PAX8 Q06710 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ PCSK9 Q8NBP7 1/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ NPSR1 Q6W5P4 1/20 0.33
▸ SIGMAR1 Q99720 2/20 0.33
▸ NQO1 P15559 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27865943 0.84 SMN1; SMN2 (0.41) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL27804824 0.82 LMNA (0.41) CSNK1ESMN1; SMN2CNR2LMNAPAX8
SCHEMBL27806107 0.81 CSNK1E (0.41) CSNK1ECNR2LMNAPAX8ALDH1A1
SCHEMBL27826684 0.81 CSNK1E (0.41) CSNK1ECNR2LMNAPAX8ALDH1A1
SCHEMBL27806097 0.81 CSNK1E (0.41) CSNK1ECNR2LMNAPAX8ALDH1A1
SCHEMBL27806110 0.81 CSNK1E (0.41) CSNK1ECNR2LMNAPAX8ALDH1A1
SCHEMBL28790610 0.81 CSNK1E (0.41) CSNK1ECNR2LMNAPAX8ALDH1A1
SCHEMBL27826821 0.81 CSNK1E (0.41) CSNK1ECNR2LMNAPAX8ALDH1A1
SCHEMBL27826669 0.81 CSNK1E (0.41) CSNK1ECNR2LMNAPAX8ALDH1A1
SCHEMBL27826656 0.81 CSNK1E (0.41) CSNK1ECNR2LMNAPAX8ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10610598-B2 Linear polyester and semi-linear glycidol polymer systems: formulation and synthesis of novel monomers and macromolecular structures VANDERBILT UNIVERSITY (US) 2020-04-07 — — US disclosed
US-20180125983-A1 Linear Polyester and Semi-Linear Glycidol Polymer Systems: Formulation and Synthesis of Novel Monomers and Macromolecular Structures UNIV VANDERBILT (US) 2018-05-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180125983-A1 Linear Polyester and Semi-Linear Glycidol Polymer Systems: Formulation and Synthesis of Novel Monomers and Macromolecular Structures STT3A, STT3B, B3GAT3 CSNK1E 4309/4885MAPT 175/4885HPGD 1749/4885
US-10610598-B2 Linear polyester and semi-linear glycidol polymer systems: formulation and synthesis of novel monomers and macromolecular structures STT3A, STT3B, B3GAT3 CSNK1E 4309/4885MAPT 175/4885HPGD 1749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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