Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.46 |
| ▸ | SFRP1 | Q8N474 | 5/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | CKS1B | P61024 | 1/20 | 0.43 |
| ▸ | SKP1 | P63208 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | WNT3 | P56703 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12632371 | 0.87 | ALDH1A1 (0.46) | ALDH1A1RAB9AKMT2ALMNASMN1; SMN2 | |
| SCHEMBL12631691 | 0.87 | ALDH1A1 (0.47) | ALDH1A1RAB9AKMT2ALMNASMN1; SMN2 | |
| SCHEMBL2013818 | 0.87 | ALDH1A1 (0.47) | ALDH1A1RAB9AKMT2ALMNASMN1; SMN2 | |
| SCHEMBL12631617 | 0.86 | ALDH1A1 (0.49) | ALDH1A1RAB9AKMT2ALMNASMN1; SMN2 | |
| SCHEMBL12631614 | 0.86 | ALDH1A1 (0.46) | SFRP1ALDH1A1RAB9AKMT2ALMNA | |
| SCHEMBL12631378 | 0.84 | ALDH1A1 (0.44) | ALDH1A1RAB9AKMT2ALMNASMN1; SMN2 | |
| SCHEMBL12632373 | 0.84 | APP (0.46) | ALDH1A1RAB9AKMT2ALMNASMN1; SMN2 | |
| SCHEMBL2012363 | 0.84 | USP30 (0.52) | SFRP1ALDH1A1RAB9AKMT2AUSP30 | |
| SCHEMBL12628525 | 0.84 | USP30 (0.52) | SFRP1ALDH1A1RAB9AKMT2AUSP30 | |
| SCHEMBL12631385 | 0.83 | APP (0.44) | KCNA3ALDH1A1RAB9AKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073277-A1 | PIPERIDINE ARYL SULFONAMIDE DERIVATIVES AS Kv1.3 MODULATORS | EVOTEC AG (DE) | 2011-06-23 | — | — | WO | claimed |