Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12631691 | 1.00 | ALDH1A1 (0.47) | ALDH1A1KMT2ARAB9AATMLMNA | |
| SCHEMBL12631617 | 0.92 | ALDH1A1 (0.49) | ALDH1A1KMT2ARAB9ALMNASMN1; SMN2 | |
| SCHEMBL12631378 | 0.89 | ALDH1A1 (0.44) | ALDH1A1KMT2ARAB9ALMNASMN1; SMN2 | |
| SCHEMBL12631681 | 0.88 | ALDH1A1 (0.47) | ALDH1A1KMT2ARAB9ALMNASMN1; SMN2 | |
| SCHEMBL12631381 | 0.88 | ALDH1A1 (0.44) | ALDH1A1KMT2ARAB9ALMNASMN1; SMN2 | |
| SCHEMBL12631379 | 0.88 | LMNA (0.44) | ALDH1A1KMT2ARAB9ALMNASMN1; SMN2 | |
| SCHEMBL2052998 | 0.88 | ALDH1A1 (0.44) | ALDH1A1KMT2ARAB9ALMNASMN1; SMN2 | |
| SCHEMBL2010903 | 0.88 | LMNA (0.44) | ALDH1A1KMT2ARAB9ALMNASMN1; SMN2 | |
| SCHEMBL2010182 | 0.87 | KMT2A (0.42) | ALDH1A1KMT2ARAB9ALMNASMN1; SMN2 | |
| SCHEMBL12632371 | 0.87 | ALDH1A1 (0.46) | ALDH1A1KMT2ARAB9ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073277-A1 | PIPERIDINE ARYL SULFONAMIDE DERIVATIVES AS Kv1.3 MODULATORS | EVOTEC AG (DE) | 2011-06-23 | — | — | WO | claimed |