SCHEMBL2013143

SCHEMBL2013143

CCOP(=O)(CC)OCN(CCO)CCO

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.56
PPARD Q03181 2/20 0.48
MEN1 O00255 1/20 0.40
GAA P10253 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
KMT2A Q03164 1/20 0.40
TDP1 Q9NUW8 2/20 0.36
ACHE P22303 1/20 0.32
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3196771 0.84 TSHR (0.54) TSHRPPARDMEN1GAACYP2C9
SCHEMBL11133898 0.81 TSHR (0.56) TSHRPPARDMEN1GAACYP2C9
SCHEMBL2540679 0.81 TSHR (0.52) TSHRPPARDMEN1GAACYP2C9
SCHEMBL530398 0.79 CYP2C9 (0.56) TSHRPPARDMEN1GAACYP2C9
SCHEMBL19979584 0.79 CYP2C9 (0.56) TSHRPPARDMEN1GAACYP2C9
SCHEMBL14790946 0.78 MEN1 (0.51) TSHRPPARDMEN1GAACYP2C9
SCHEMBL8113767 0.77 PPARD (0.63) TSHRPPARDMEN1GAACYP2C9
SCHEMBL16625359 0.77 PPARD (0.63) TSHRPPARDMEN1GAACYP2C9
SCHEMBL16625363 0.76 PPARD (0.57) TSHRPPARDMEN1GAACYP2C9
Trolamine SCHEMBL9232394 0.76 PPARD (0.48) TSHRPPARDMEN1GAACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230391669-A1 METHOD FOR PREPARING GROUTING REINFORCEMENT FILLER FOR MINING CCTEG CHINA COAL Research Institute (CN) 2023-12-07 US claimed
EP-3658605-B1 RIGID POLYURETHANE FOAM CONTAINING REACTIVE FLAME RETARDANT ICL IP AMERICA INC (US) 2023-06-14 EP claimed
US-11352479-B2 Rigid polyurethane foam containing reactive flame retardant ICL-IP AMERICA INC. (US) 2022-06-07 US claimed
US-20210079301-A1 RIGID POLYURETHANE FOAM CONTAINING REACTIVE FLAME RETARDANT ICL-IP AMERICA INC. 2021-03-18 US claimed
EP-3783042-A1 RIGID POLYURETHANE FOAM CONTAINING REACTIVE FLAME RETARDANT ICL-IP America Inc. (US) 2021-02-24 EP claimed
EP-3658605-A1 RIGID POLYURETHANE FOAM CONTAINING REACTIVE FLAME RETARDANT ICL-IP America Inc. (US) 2020-06-03 EP claimed
EP-2892937-B1 RIGID FOAMS SUITABLE FOR WALL INSULATION COVESTRO LLC (US) 2019-06-05 EP claimed
WO-2019023091-A1 RIGID POLYURETHANE FOAM CONTAINING REACTIVE FLAME RETARDANT ICL-IP AMERICA INC. (US) 2019-01-31 WO claimed
US-9963806-B2 Dyeable and flame-retarded thermoplastic polyurethane fibers LUBRIZOL ADVANCED MATERIALS, INC. (US) 2018-05-08 US claimed
EP-2841282-B1 FABRIC PRINT MEDIA HEWLETT PACKARD DEVELOPMENT CO LP (US) 2017-11-01 EP claimed
US-7713450-B2 Photocromic primer composition having high impact resistance and transparent material coated with the same LG CHEM. LTD. (KR) 2010-05-11 US claimed
US-20070275234-A1 Photocromic Primer Composition Having High Impact Resistance and Transparent Material Coated With the Same LG CHEM, LTD. (KR) 2007-11-29 US claimed
US-20070227748-A1 Fire Retarded Flexible Nanocomposite Polyurethane Foams UNIVERSITY OF STRATHCLYDE (GB) 2007-10-04 US claimed
US-7193226-B2 Scratch resistant moisture-protecting parylene layers AGFA-GEVAERT (BE) 2007-03-20 US claimed
US-20050067584-A1 Scratch resistant moisture-protecting parylene layers AGFA NV (BE) 2005-03-31 US claimed
US-20050054553-A1 Liquid fabric softening compositions comprising flame retardant THE PROCTER & GAMBLE COMPANY 2005-03-10 US claimed
EP-0581843-A1 BIODEGRADABLE COMPOSITIONS COMPRISING STARCH PARKE DAVIS AND COMPANY (US) 1994-02-09 EP claimed
EP-0578759-A1 BIODEGRADABLE COMPOSITIONS COMPRISING STARCH DERIVATIVES PARKE, DAVIS & COMPANY (US) 1994-01-19 EP claimed
WO-1992016583-A1 BIODEGRADABLE COMPOSITIONS COMPRISING STARCH DERIVATIVES PARKE, DAVIS & COMPANY (US) 1992-10-01 WO claimed
WO-1992016584-A1 BIODEGRADABLE COMPOSITIONS COMPRISING STARCH PARKE, DAVIS & COMPANY (US) 1992-10-01 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210079301-A1 RIGID POLYURETHANE FOAM CONTAINING REACTIVE FLAME RETARDANT PFAS, PFKFB3, PUF60 TSHR 3175/4885PPARD 408/4885MEN1 4227/4885
US-11352479-B2 Rigid polyurethane foam containing reactive flame retardant PFAS, PFKFB3, PUF60 TSHR 3175/4885PPARD 408/4885MEN1 4227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.