SCHEMBL2540679

SCHEMBL2540679

CCOP(=O)(OCC)OCN(CCO)CCO

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
PPARD Q03181 2/20 0.42
MEN1 O00255 2/20 0.35
GAA P10253 2/20 0.35
KMT2A Q03164 2/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
TDP1 Q9NUW8 2/20 0.33
TP53 P04637 1/20 0.33
POLB P06746 1/20 0.32
CYP3A4 P08684 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HTT P42858 1/20 0.31
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5010313 0.89 KDM4E (0.32) TSHRPPARD
SCHEMBL11168782 0.82 TSHR (0.50) TSHRPPARDMEN1GAAKMT2A
SCHEMBL2013143 0.81 TSHR (0.56) TSHRPPARDMEN1GAAKMT2A
Triethyl Phosphate SCHEMBL28143347 0.78 TSHR (0.77) TSHRPPARDTDP1TP53CYP3A4
Trolamine SCHEMBL9232394 0.75 PPARD (0.48) TSHRPPARDMEN1GAAKMT2A
Triethyl Phosphate SCHEMBL28464376 0.75 TSHR (0.81) TSHRPPARDTDP1TP53CYP3A4
SCHEMBL28466410 0.74 TSHR (0.62) TSHRPPARDMEN1GAAKMT2A
SCHEMBL5010316 0.74 TPI1 (0.32) PPARD
SCHEMBL530398 0.73 CYP2C9 (0.56) TSHRPPARDMEN1GAAKMT2A
SCHEMBL19979584 0.73 CYP2C9 (0.56) TSHRPPARDMEN1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6713168-B2 ORGANOPHOSPHORUS ESTER COMPOUND AND A POLYMER BINDER RESIN J.M. HUBER CORPORATION 2004-03-30 US claimed
US-20030064230-A1 Fire retardant wood composite materials and methods for making the same HUBER ENGINEERED WOODS LLC 2003-04-03 US claimed
US-RE31757-E Composition and a method for controlling reaction pressures during the foaming process resulting in an easily flame retarded foam-in place insulation Crehan, Patrick J. (US) 1984-12-04 US claimed
US-4291129-A Composition and a method for controlling reaction pressures during the foaming process resulting in an easily flame retarded foam-in place insulation Crehan, Patrick James. (US) 1981-09-22 US claimed
CN-121378648-A Aqueous polyurethane emulsion and preparation method and application thereof 上海飞顿新材料科技有限公司 2026-01-23 CN disclosed
EP-3259294-B1 HIGH TEMPERATURE RESISTANT FOAMS COVESTRO DEUTSCHLAND AG (DE) 2019-12-18 EP disclosed
EP-3259294-A1 FOAM MATERIALS RESISTANT TO HIGH TEMPERATURES Covestro Deutschland AG (DE) 2017-12-27 EP disclosed
WO-2016131878-A1 FOAM MATERIALS RESISTANT TO HIGH TEMPERATURES COVESTRO DEUTSCHLAND AG (DE) 2016-08-25 WO disclosed
US-9365717-B2 Carboxyl group-containing polyimide, thermosetting resin composition and flexible metal-clad laminate TOYOBO CO., LTD. (JP) 2016-06-14 US disclosed
EP-2716674-B1 CARBOXYL GROUP-CONTAINING POLYIMIDE, HEAT-CURABLE RESIN COMPOSITION, AND FLEXIBLE METAL-CLAD LAMINATE TOYO BOSEKI (JP) 2016-04-27 EP disclosed
US-20150183760-A1 THERAPEUTIC COMPOUNDS AND COMPOSITIONS AGIOS PHARMACEUTICALS, INC (US) 2015-07-02 US disclosed
CN-104204016-A Process for preparing rigid polyurethane foams and rigid polyisocyanurate foams BASF SE 2014-12-10 CN disclosed
EP-1605002-A1 HYDROGENATED DIENE COPOLYMER, POLYMER COMPOSITION, AND MOLDED OBJECT JSR Corporation (JP) 2005-12-14 EP disclosed
US-6939610-B1 Thermal insulating coating for spacecrafts THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 2005-09-06 US disclosed
WO-2005071004-A2 FLAME RETARDANT POYLMER COMPOSITIONS THE BOEING COMPANY (US) 2005-08-04 WO disclosed
US-20050049338-A1 Flame retardant polymer compositions BOEING COMPANY, THE 2005-03-03 US disclosed
US-20040025743-A1 Curable composition, varnish, and layered product ZEON CORPORATION (JP) 2004-02-12 US disclosed
EP-0146897-B1 MAGNETIC RECORDING MEDIUM SONY CORPORATION (JP) 1989-08-30 EP disclosed
US-4656200-A Phosphonic acid salts as flame retardants for polyurethanes and polyisocyanurates CIBA-GEIGY AG (CH) 1987-04-07 US disclosed
EP-0146897-A2 Magnetic recording medium SONY CORPORATION (JP) 1985-07-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150183760-A1 THERAPEUTIC COMPOUNDS AND COMPOSITIONS PDK1, PDK2, PDK3 TSHR 2017/4885PPARD 188/4885MEN1 3010/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.