Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BID | P55957 | 3/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.45 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.45 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | EP300 | Q09472 | 1/20 | 0.45 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.45 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.45 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.42 |
| ▸ | PLK1 | P53350 | 2/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.41 |
| ▸ | RARB | P10826 | 2/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7654179 | 0.95 | BID (0.44) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL7653867 | 0.95 | BID (0.44) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL7863490 | 0.93 | HCAR2 (0.42) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL29927198 | 0.87 | HCAR2 (0.47) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL7855513 | 0.87 | HCAR2 (0.47) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL5588159 | 0.86 | BID (0.44) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL5589999 | 0.86 | BID (0.44) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL5589378 | 0.86 | BID (0.44) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL5589987 | 0.86 | BID (0.44) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL5588795 | 0.86 | BID (0.44) | BIDMCL1BCL2L1BAK1KAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9745252-B2 | Cross-linking moiety | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2017-08-29 | — | — | US | disclosed |
| US-9745252-B2 | Cross-linking moiety | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2017-08-29 | — | — | US | disclosed |
| EP-2507309-A1 | A CROSS-LINKING MOIETY | National University of Singapore (SG) | 2012-10-10 | — | — | EP | disclosed |
| US-20120244294-A1 | CROSS-LINKING MOIETY | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2012-09-27 | — | — | US | disclosed |
| US-20120244294-A1 | CROSS-LINKING MOIETY | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2012-09-27 | — | — | US | disclosed |
| WO-2011068482-A1 | A CROSS-LINKING MOIETY | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2011-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120244294-A1 | CROSS-LINKING MOIETY | ARF1, ARF6, ARF4 | BID 3633/4885MCL1 376/4885BCL2L1 1655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.