Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 4/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | MEF2D | Q14814 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.33 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.32 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20129870 | 0.83 | KCNQ3 (0.43) | KCNQ3KCNQ2MEN1MAPTKMT2A | |
| SCHEMBL20129861 | 0.82 | BACE1 (0.46) | KCNQ3KCNQ2MEN1MAPTKMT2A | |
| SCHEMBL20129864 | 0.81 | APP (0.48) | KCNQ3KCNQ2HDAC3RPS6KB1APP | |
| SCHEMBL29721496 | 0.81 | APP (0.48) | KCNQ3KCNQ2HDAC3RPS6KB1APP | |
| SCHEMBL17749119 | 0.81 | KCNQ3 (0.34) | KCNQ3KCNQ2MEN1MAPTKMT2A | |
| SCHEMBL23711052 | 0.81 | KCNQ3 (0.34) | KCNQ3KCNQ2MEN1MAPTKMT2A | |
| SCHEMBL17749207 | 0.75 | KCNQ3 (0.56) | KCNQ3KCNQ2MEN1MAPTKMT2A | |
| SCHEMBL20129875 | 0.73 | KCNQ2 (0.50) | KCNQ3KCNQ2MEN1MAPTKMT2A | |
| SCHEMBL20129866 | 0.71 | KCNQ3 (0.43) | KCNQ3KCNQ2MEN1MAPTKMT2A | |
| SCHEMBL17749144 | 0.71 | KCNQ2 (0.60) | KCNQ3KCNQ2HDAC3APPKCNQ4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180127357-A1 | (2-AMINO-4-(ARYLAMINO)PHENYL) CARBAMATES | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180127357-A1 | (2-AMINO-4-(ARYLAMINO)PHENYL) CARBAMATES | HRH4, H1-10, HDAC10 | KCNQ3 1235/4885KCNQ2 1257/4885MEN1 1794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.