Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.45 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.43 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2012449 | 0.82 | HCAR3 (0.45) | KDM4EKMT2AGAAALDH1A1HSD17B10 | |
| SCHEMBL30622603 | 0.82 | HCAR3 (0.45) | KDM4EKMT2AGAAALDH1A1HSD17B10 | |
| SCHEMBL8953225 | 0.80 | KDM4E (0.38) | NR4A2KDM4EKMT2ALMNATSHR | |
| SCHEMBL17921441 | 0.76 | NR4A2 (0.50) | NR4A2KDM4EKMT2AGAALMNA | |
| SCHEMBL17910027 | 0.76 | KMT2A (0.37) | NR4A2KDM4EKMT2AGAAALDH1A1 | |
| SCHEMBL30618046 | 0.76 | KMT2A (0.37) | NR4A2KDM4EKMT2AGAAALDH1A1 | |
| SCHEMBL28443183 | 0.76 | KDM4E (0.35) | NR4A2KDM4EKMT2ALMNAALDH1A1 | |
| SCHEMBL2014506 | 0.75 | KDM4E (0.43) | NR4A2KDM4EKMT2AATMGAA | |
| SCHEMBL3072756 | 0.75 | NR4A2 (0.49) | NR4A2FGFR1PKN1PKN2KDM4E | |
| SCHEMBL7477385 | 0.74 | PARP1 (0.49) | NR4A2PKN1PKN2KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073316-A1 | 4-ARYL-BUTANE-1,3-DIAMIDES | NOVARTIS AG (CH) | 2011-06-23 | — | — | WO | disclosed |
| WO-2011073316-A1 | 4-ARYL-BUTANE-1,3-DIAMIDES | NOVARTIS AG (CH) | 2011-06-23 | — | — | WO | disclosed |