Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8953225 | 0.80 | KDM4E (0.38) | KDM4EALDH1A1NR4A2HCAR3NPC1 | |
| SCHEMBL28897492 | 0.79 | L3MBTL1 (0.41) | KDM4EALDH1A1NR4A2NPC1RAB9A | |
| SCHEMBL2013415 | 0.76 | NR4A2 (0.45) | KDM4EALDH1A1NR4A2NPC1RAB9A | |
| SCHEMBL17910027 | 0.70 | KMT2A (0.37) | KDM4EALDH1A1NR4A2HCAR3HSD17B10 | |
| SCHEMBL30618046 | 0.70 | KMT2A (0.37) | KDM4EALDH1A1NR4A2HCAR3HSD17B10 | |
| SCHEMBL28448806 | 0.69 | KMT2A (0.41) | KDM4EALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL28448807 | 0.69 | ALDH1A1 (0.41) | KDM4EALDH1A1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL29041518 | 0.69 | LMNA (0.52) | KDM4EALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL1354809 | 0.69 | KDM4E (0.38) | KDM4EALDH1A1NR4A2NPC1RAB9A | |
| SCHEMBL8524627 | 0.68 | NNMT (0.39) | KDM4EALDH1A1HCAR3NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111606928-A | Azacyclodiketone compound and preparation method thereof | 维清生物科技(上海)有限公司 | 2020-09-01 | — | — | CN | disclosed |