Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15260808 | 1.00 | FAAH (0.37) | FAAHSLC6A4SLC6A2SLC6A3TRPV1 | |
| SCHEMBL15261521 | 0.87 | FAAH (0.38) | FAAHSLC6A4SLC6A2SLC6A3TRPV1 | |
| SCHEMBL30467136 | 0.87 | FAAH (0.38) | FAAHSLC6A4SLC6A2SLC6A3TRPV1 | |
| SCHEMBL15229243 | 0.87 | FAAH (0.38) | FAAHSLC6A4SLC6A2SLC6A3TRPV1 | |
| SCHEMBL15274780 | 0.86 | SLC6A4 (0.33) | SLC6A4SLC6A2SLC6A3APPCCNA2 | |
| SCHEMBL12450723 | 0.82 | CES2 (0.32) | CYP3A4CYP2C9 | |
| SCHEMBL15232113 | 0.79 | SLC6A4 (0.33) | SLC6A4SLC6A2SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL15229305 | 0.79 | SLC6A4 (0.33) | SLC6A4SLC6A2SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL15260365 | 0.79 | FAAH (0.39) | FAAHTRPV1APPCCNA2CDK2 | |
| SCHEMBL20134701 | 0.77 | SLC6A2 (0.40) | FAAHSLC6A4SLC6A2SLC6A3APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106349217-B | Serine/threonine kinase inhibitors | 阵列生物制药公司 | 2020-08-28 | — | — | CN | disclosed |
| EP-3321262-A1 | SERINE/THREONINE KINASE INHIBITORS | Array Biopharma, Inc. (US) | 2018-05-16 | — | — | EP | disclosed |